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Volume : 5 Issue : 1 Year : 2022

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Effect of Aerobic Exercise Program on Inflammatory Parameters and Framingham Risk Score in High Cardiac Risk Patients [anatol j fm]
anatol j fm. 2022; 5(1): 38-43 | DOI: 10.5505/anatoljfm.2021.06078

Effect of Aerobic Exercise Program on Inflammatory Parameters and Framingham Risk Score in High Cardiac Risk Patients

Nart Zafer Baytuğan1, Hasan Çağlayan Kandemir2
1Department of Cardiology, Gebze Fatih State Hospital, Kocaeli, Turkey
2Department of Cardiology, Kocaeli Public Hospital, Kocaeli, Turkey

INTRODUCTION: The aim of this study was to determine the effects of an 8-week aerobic exercise program on the inflammatory parameters and the Framingham risk score in patients with high cardiac risk.
METHODS: The patients with high cardiac risk according to National Cholesterol Education Program Adult Treatment Panel-3 criteria were studied. Totally, 50 patients were included in the study, and 25 (50.0%) patients were applied to an aerobic exercise program for 30 min/day for 3 days a week. There were 25 (50.0%) patients in the control group.
RESULTS: The study included 50 patients and the mean age of the patients was 61.0±5.0 years. At the end of the study, hs-CRP levels decreased in the exercise group [1.1 (0.1–4.2) mg/dL vs 0.9 (0.1–3.8) mg/dL] and in the control group [1.2 (0.2–4.3) mg/dL vs 1.0 (0.1–4.0) mg/dL] (<0.001 and p=0.008, respectively). Homocysteine levels [13.4 (4.8–27.3) μmol/L vs 11.8 (4.0–21.6) μmol/L] decreased in the exercise group, but they did not change in the control group [13.2 (5.1–28.2) μmol/L vs 13.4 (4.4–27.1) μmol/L](p<0.001, and p=0.776, respectively). Fibrinogen levels decreased in the exercise group [4.1 (1.6–5.9 g/L vs 3.4 (1.2–5.0) g/L], but they did not change in the control group [4.0 (1.4–6.1) g/L vs 3.9 (1.4–5.7) g/L] (p<0.001 and p=0.348, respectively). The Framingham risk score decreased in the exercise [24.1±2.9 vs 20.3±3.3] and control groups [22.8±2.7 vs 19.5±2.7] (p<0.001 and p<0.001, respectively).
DISCUSSION AND CONCLUSION: Regular aerobic exercise is effective and safe to prevent probable cardiovascular events in high cardiac risk patients in addition to medical therapy.

Keywords: Exercise, C-reactive protein, fibrinogen, homocysteine.

Nart Zafer Baytuğan, Hasan Çağlayan Kandemir. Effect of Aerobic Exercise Program on Inflammatory Parameters and Framingham Risk Score in High Cardiac Risk Patients. anatol j fm. 2022; 5(1): 38-43

Corresponding Author: Nart Zafer Baytuğan, Türkiye
Manuscript Language: English
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